Endocrine Abstracts

Carotid intima–media thickness (IMT) has been shown an independent predictive marker of coronary artery disease (CAD) and cardiovascular disease in many studies. We investigated the usefulness of carotid IMT as a screening test for CAD in Korean diabetic patients. We conducted retrospective study and found the type 2 diabetic patients without cardiovascular disease history who underwent carotid ultrasonography (US) and stress echocardiography (SE) from June 2006 to Decemb...

Aims: HDL have many diverse functions. The goal of this study was to determine the differential effect of HDL cholesterol (HDL-C) and apolipoprotein A-I (apoA-I) on the development of type 2 diabetes (T2D). In addition, this study determined the association between the ratio of HDL-C to apoA-I (HA) and incident T2D.Methods: A total of 27 988 subjects with impaired fasting glucose (IFG) (18 266 men and 9722 women) aged 21 to 91 years (mean age 43.5 years)...

Objective: The association between albuminuria and peripheral artery disease (PAD) could be confounded by renal function. Albuminuria reflects generalized disruption of endothelial cell function. This study was conducted to examine the association of PAD with low glomerular filtration rate (GFR) and albuminuria in diabetic patients.Methods: A total of 254 diabetic patients were included. We examined the age, sex, duration of diabetes, GFR, urinary albumi...

Background: A variety of insulin analogs have been developed and used for the treatment of diabetes mellitus. We often experience elevated serum insulin levels when insulin analog is used, and thus have difficulty in assessing insulin resistance and secretion using serum insulin results. This study aimed to investigate the differences in serum fasting insulin level and insulin antibodies according to the type of insulin analogs.Method: We conducted a ret...

Background: Lipoprotein (a) (Lp(a)) is a low-density lipoprotein like particle which has proatherogenic and a prothrombotic properties. Therefore, increased Lp(a) levels have been reported to be associated with a higher cardiovascular risk in numerous studies. However, the association between Lp(a) and metabolic disorders such as diabetes or metabolic syndrome (MetS) is still controversial. This study aimed to examine the association between Lp(a) levels and presence of MetS i...

Purpose: Aster spathulifolius Maxim is one of plants of chrysanthemum, which has shown an anti-obesity activity in diet induced mice model. We performed clinical trial for evaluating the anti-obesity efficacy and safety of Aster spathulifolius Maxim extract on obese human.Methods: This study was randomised, double-blind, placebo-controlled clinical trial in Korea. A total of 41 obese subjects (BMI 25–30 kg/m2) aged ≥20 years were ra...